Sea Buckthorn Oil (96%)
—Dietary Supplement

We opted for a formula that is short but highly concentrated in active ingredients.

Let it be the essentials—and nothing but the essentials!

• Organic sea buckthorn berry oil from our plantation: 118 mg per spray, rich in omega-7
• Plant-based vitamin D3 derived from lichen: 5 µg (equivalent to 200 IU per spray)
• Vitamin E: 3.4 mg (including 3 mg of vitamin E)

Sea buckthorn berry oil from our organic plantation provides a lipid matrix rich in omega-7, known for its role in protecting tissues and modulating inflammation. Combined with vitamin D3, which is essential for immune function, and vitamin E, a leading antioxidant, it forms a simple yet comprehensive foundation to support the body as it adapts to seasonal changes.

Solvent-free enzymatic extraction • 100% natural & vegan formula • Made in France • No unnecessary additives • No added sugar •

The combination of omega-7 fatty acids naturally found in our sea buckthorn oil, plant-based vitamin D3, and antioxidant vitamin E helps support the body’s natural defenses and boost the immune response on a daily basis. This concise, highly concentrated formula is designed to provide stability, vitality, and protection throughout the cold season.

We chose authenticity by opting for a spray format rather than a gel or capsule format.

We do not seek to convey the impression of a medication by using capsules or softgels. We embrace a plant-based, natural, and effective identity. The sublingual spray allows for precise dosing and direct contact with the raw material.

It preserves the bioavailability of the active ingredients and highlights the quality of our ingredients.

We prioritize the quality and purity of our raw materials over the marketing of a useless and costly format.

Our recommendations

Shake well before use.

Adults: 4 sprays per day during the winter to support your immune system. If you have a deficiency, you may increase the dose to 10 sprays per day, in consultation with your doctor.

Children: Ages 4 and up: 1 to 3 sprays per day, as needed.

This flexibility allows you to adjust your dosage based on the season, your lifestyle, and fluctuations in energy levels. The spray format also makes it easier for people who prefer to avoid pills and capsules.

Precautions

Follow the recommended dosage. Not recommended for people taking anticoagulant medication. Dietary supplements are not a substitute for a varied diet, adequate sleep, and a healthy lifestyle. Keep out of reach of children.

Preservation

Store the bottle at room temperature, away from heat and light. Excessive exposure can alter the fatty acids and reduce the oil’s nutritional quality. Best consumed within three months of opening to fully preserve the freshness of the fats and vitamins.

Sea Buckthorn Pulp and Seed Oil and Immune System Support

Subjects/duration: murine model of cyclophosphamide-induced immunosuppression, supplementation with sea buckthorn pulp oil.

What was measured: NK cell activity, macrophage phagocytosis, lymphocyte proliferation, cytokine production (IL-2, IL-4, IL-12, TNF-α, etc.).

Result: Sea buckthorn pulp oil enhances the immune response (more active NK cells and macrophages, increased levels of immune cytokines) compared to the control group.

Key takeaway: In this model of immunosuppression, sea buckthorn oil supports several key aspects of innate and adaptive immunity.

Source: Zhang J. et al., Food & Function, 2021.

Sea buckthorn, inflammation, and cardiovascular protection

Who / Duration: A review of recent literature on Hippophae rhamnoides L. and the prevention or treatment of cardiovascular diseases.

What was analyzed: clinical and preclinical data on the effects of sea buckthorn on blood lipids, inflammation, oxidative stress, and the gut microbiota.

Result: Sea buckthorn extracts and oils have been shown to have anti-inflammatory and antioxidant effects and to favorably modulate certain metabolic markers and the microbiota in various animal models and human studies.

Key takeaway: The bioactive compounds in sea buckthorn (omega fatty acids, polyphenols, carotenoids) help reduce underlying systemic inflammation and protect the cardiovascular system.

Source: Chen Y. et al., Frontiers in Cardiovascular Medicine, 2024.

A Comprehensive Review of Sea Buckthorn: Omega-3 Fatty Acids, Antioxidants, and Inflammation

Who / Duration: Review article on Hippophae rhamnoides L. (composition, nutrients, nutritional and therapeutic uses).

The following were analyzed: levels of omega-3, 6, 7, and 9 fatty acids, carotenoids, vitamin E, and polyphenols, as well as available data on inflammation, oxidation, and tissue protection.

Result: Sea buckthorn is notable for its high content of omega-7 and antioxidants, with documented effects on modulating inflammation and protecting the mucous membranes and skin, as shown in various preclinical and clinical studies.

Key takeaway: Sea buckthorn is a particularly valuable lipid matrix for supporting the skin barrier, mucous membranes, and certain immune and inflammatory parameters.

Source: Surya Prakash H. et al., Pharmacognosy Reviews, 2024.

Vitamin D3 and Immune Function

Who / Duration: A review and meta-analysis involving more than 10,000 participants from multiple clinical trials and observational studies.

What was analyzed: the relationship between vitamin D status, supplementation, and the risk of infections (particularly respiratory infections), as well as markers of the immune response.

Result: Vitamin D deficiency is consistently associated with a higher risk of acute infections, while supplementation has been shown in several studies to have a moderate but real protective effect, particularly in individuals with a deficiency.

Key takeaway: Vitamin D3 acts as an immune modulator, and adequate levels appear to help boost resistance to certain infections, particularly respiratory infections.

Source: Martens P.J. et al., Nutrients, 2020.

Vitamin D3, baseline levels, and risk of infection

Participants / duration: a randomized controlled trial involving 412 young men, with measurements of 25(OH)D levels and episodes of respiratory tract infections over a 14-week period.

What was measured: the incidence of acute respiratory infections, cathelicidin (an antimicrobial peptide) levels, and vitamin D deficiency.

Results: Vitamin D deficiency (25(OH)D levels below 50 nmol/L) is associated with an approximately twofold increased risk of respiratory infections (OR close to 2.1), while supplementation appears to be most beneficial for those with the most severe deficiency.

Key takeaway: Vitamin D3 appears to be particularly important for people with a known deficiency, who are at higher risk of infection. Appropriate supplementation partially reduces this risk.

Source: Laaksi A. et al., Open Forum Infectious Diseases, 2024.

Transparency Note

This research focuses on independent reviews and clinical trials. It does not directly evaluate L’Invincible, but sheds light on the selection of its ingredients: sea buckthorn berry oil, rich in lipids and antioxidants, vitamin D3, and vitamin E. The doses, durations, and study populations vary from one study to another. The key takeaway is the overall consistency: sea buckthorn and vitamin D3 are two well-documented pillars for supporting certain immune parameters, chronic inflammation, and the body’s resistance to external stressors.